Rare cancers, also known as rare tumors or orphan cancers, are types of cancer that occur infrequently. Each specific type of rare cancer is uncommon, but collectively, rare cancers account for a significant portion of cancer cases. Due to their rarity, these cancers often pose challenges in terms of diagnosis, treatment, and research. While rare cancers present unique challenges, ongoing efforts in research, collaboration, and patient advocacy aim to improve outcomes and quality of life for individuals affected by these uncommon malignancies. Patients with rare cancers often benefit from support groups, online communities, and advocacy organizations that can provide information, resources, and a sense of community.